2nd Mouse Imaging Master Class

About

The short school gives the opportunity to learn more about image-based phenotyping using a wide variety of methods to characterize morphologically and functionally disease models. This PATHBIO module will cover the “state of art” for the most relevant imaging techniques used in mice, such as X-ray, microCT, MRI, OPT, HREM, optoacoustic imaging, echography, intravital microscopy, as well as the basis for image analysis and 3D rendering.

Most of these imaging techniques are translational from the human clinic as the technologies were initially developed for assessing human patients and later adapted to mouse models. The course teaching will combine lectures and workshop in which participants will learn how to use Image J for analysis, discern and discuss the processing and the analyzing methods between OPT, HREM, micro-CT & MRI, and finally understand how to take advantage of these imaging methods to answer your scientific questions, specifically focusing on the 3’R criteria (Refinement, Replacement and Reduction), ethics and animal welfare.

Course leader

PATHBIO, an EU-funded ERASMUS+ Knowledge Alliance for “Precision Pathobiology for Disease Models”, involving 20 partners from all over the world.

Target group

30 attendees, selected upon motivations and belonging to Graduate master, PhD and postdoc students and reserachers.

Course aim

The aim is to provide graduate, master, PhD and postdoc students with basic and expert knowledge to phenotype morphologically mouse models of human diseases. Imaging offers the opportunity to characterize further the features with a wide variety of methods and they are almost translational, with most of them primarily developed in human and adapted to animal models. The invited experts, mouse embryologists, anatomists, pathologists and researchers from Europe, Asia, and Canada will give lectures and discuss with you different aspects of mouse Imaging technologies providing powerful tools to understand and follow the progress of diseases and how to take advantage of these imaging methods to answer your scientific questions, specifically focusing on the 3’R criteria (Refinement, Replacement and Reduction), ethics and animal welfare.

It will be a unique chance to understand the basic principles of several key methods from structural to functional imaging and to get an overview of the best practices including the 3’R rules to design scientific experiments.